Why ethylene oxide final sterilisation

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WHY ETHYLENE OXIDE FINAL STERILISATION

After the crosslinking process and machining, the final implant has to be sterilised.
It is evident, that in order to prevent new free radical formation and subsequent oxidation, an inert final sterilisation process with ethylene oxide (or gas plasma) must be used.
Any sterilisation process involving gamma rays (even in an inert environment, such as nitrogen or vacuum) must be avoided1.



1 Muratoglu, O.K., Bragdon, C.R., O’Connor, D.O., Delaney, J., Jasty, M., Harris, W.H., 2000. “The comparison of the wear behaviour of four types of crosslinked acetabular components”, 46th Annual Meeting, ORS, March 12-15 2000, Orlando, Florida.